Über den Bau der Nervenfasern und Nervenzellen beim Flusskrebs. Offprint.
by Freud, Sigmund
1882. Freud, Sigmund (1856-1939). Über den Bau der Nervenfasern und Nervenzellen beim Flusskrebs. Offprint from Sitzungsberichte der kaiserlichen Akadademie der Wissenschaften, 3 Abth., 85 (1882). 37pp. Folding lithographed plate by F. Schima after Freud. [Vienna: K.k. Hof- und Staatsdruckerei, 1882]. 242 x 155 mm., unopened. Original brown printed wrappers, small chip at foot of spine, small stain on back wrapper. Very good. Presentation Copy, inscribed by Freud to Josef Herzig (1853-1924) on the front wrapper: “Seinem lieben Freunde Dr. Josef Herzig d. Verf.” The Haskell F. Norman copy, with his bookplate. First Edition, Rare Offprint Issue. Freud made two significant contributions to neurology in his paper on nerve cells in crayfish, which Shepherd characterizes as “Freud’s most mature work on the microscopic structure of nerve cells” (Shepherd, Foundations of the Neuron Doctrine: 25th Anniversary Edition, p. 67). First, Freud was able to demonstrate that the nerve fiber, which we now call the axon, is an outgrowth of the cell body; this is illustrated in the folding plate, which reproduces Freud’s drawings of the structures in question. “Freud thus became a pioneer of neurobiology, and of crustacean neurobiology in particular” (Wiese, Frontiers in Crustacean Neurobiology, p. 4). Second, Freud was able to confirm Robert Remak’s observations of the delicate fibrils in the axon of the nerve cell, the existence of which had been disputed since the publication of Remak’s paper on them in 1844. “Freud was able to discern separate fine fibrils following straight courses within the nerve fibers, as well as concentric loops of striae surrounding the nuclei and converging towards the processes of the cell bodies in crayfish nervous tissue . . . Electron microscopy of the crustacean nervous system confirmed Freud’s main points, which in turn vindicated those of Remak. Both researchers were looking at small bundles of microtubules, and thus they were among the first to picture the lacy intracellular framework that future cell biologists would call the cytoskeleton“ (Frixione, “Sigmund Freud’s contribution to the history of the neuronal cytoskeleton [abstract],” Journal of the History of the Neurosciences 12 : 12-24). Freud presented this copy to Josef Herzig, professor of chemistry at the University of Vienna and one of Freud’s lifelong friends. Gay, Freud: A Life for our Time. Grinstein 5. Jones I, pp. 53-54. Norman F5. (Inventory #: 44066)
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