Dissertatio epistolaris de glandulis conglobatis durae meningis humanae
by Pacchionus, Antonio
Rome: Typis Io. Francisci Buagni, 1705. Pacchioni, Antonio (1665-1726). Dissertatio epistolaris de glandulis conglobatis durae meningis humanae . . . Lucae Schrokio viro clarissimo . . . 8vo. 32pp. Folding engraved plate. Rome: Typis Io. Francisci Buagni, 1705. 160 x 106 mm. Later patterned carta rustica boards, light wear at spine. Fine copy. “Ex Ignatii Vettori libris” in 18th-century hand on title; old library stamp. Extremely Rare First Edition, with only two U. S. (Stanford, N. Y. Acad. Med.) and four European copies cited in OCLC. Pacchioni’s work contains his classic description and illustration of the Pacchionian bodies of the arachnoid tissue under the dura, which allow cerebrospinal fluid to exit the sub-arachnoid space and enter the blood stream. “The arachnoid granulations of villi had been seen by Vesalius and others, but the first adequate account of them was made by Antonio Pacchioni of Rome; his name is today associated with the very large villi which are few in number and present only in the adult. In his monograph (Dissertatio epistolae . . . ) he claimed that the villi were lymph-producing glands” (Clarke and O’Malley, The Human Brain and Spinal Cord, p. 740). There are two issues of this work, one with the title reading as above and the other with title reading Dissertatio epistolaris ad Lucam Schroeckium de glandulis conglobatis durae meningis humanae. Both are very rare. Brunori et al., “Antonio Pacchioni (1665-1726): Early studies of the dura mater,” in Journal of Neurosurgery 78 (1993): 515-518. Dictionary of Scientific Biography. Garrison-Morton.com 1380. (Inventory #: 44046)
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