Modus pharmacandi, in deme beschrieben und gelehrt wirt was der Artzt in dem menschen zu purgieren hab...
Title printed in black & red. 4 p.l., xxxi leaves, one blank leaf. Small 4to, attractive antique calf (light browning), gilt. Cologne: J. Gennep, 1562. First edition of one of the rarest publications of Paracelsus; WorldCat locates only the Washington University copy in the U.S. and it is most uncommon in European libraries. The Modus pharmacandi, written about 1527, represents Paracelsus' new modes of therapy in which he employed pharmacological resources. He can be considered a father of modern pharmacology because of his work in the chemical treatment of medical ailments. Paracelsus "directed his treatment specifically against the agent of the disease, rather than resorting to the general anti-humoral measures (such as sweating, purging, bloodletting, and inducing vomiting) that had been paramount in ancient therapy for 'removal of excess and addition of the deficient.' For Galenic remedies derived from plants, he substituted specifics, often applied on homeopathic principles. Here his notion of 'signatures' came into play, in the selection of herbs that in color and shape resembled the affected organ...Paracelsus' search for such specific medicines led him to attempt to isolate the efficient kernel (the quinta essentia) of each substance. His method was thus one of separating drugs into their component parts, rather than compounding them as the ancients had done."-D.S.B., X, pp. 307-08. Fine copy. This is the first copy of this book I have handled. ❧ Partington, II, p. 125. Sudhoff 48. Ernst Weil, Cat. 24, 192-"one of the rarest books of Paracelsus." . (Inventory #: HillBibl-5448)
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