Latent Cancer of the Stomach (with Thomas McCrae). [Offprint].
by OSLER, Sir William (1849-1919).
Philadelphia:: Philadelphia Medical Journal, 1900., 1900. Series: Philadelphia Medical Journal, Feb. 3, 1900. Offprint. 21 cm. 9,  pp. Printed wrappers. Very good. "In the early 1900s, Osler was a co-author in a review of 150 cases of cancer of the stomach published in the Philadelphia Medical Journal. The authors published a monograph on the same topic, based on the clinical and pathological records of the Johns Hopkins Hospital. He also published two articles on gastric cancer in young people. In 1898, Osler's views on cancer of the stomach were that it may rarely develop in a simple ulcer, and that gradual failure of health and death may occur without any suspicion of underlying malignant disease (8). Diagnosis depended on progressive anemia, weight loss, emaciation, intractable dyspepsia, coffee ground vomitus, absence of free hydrochloric acid and confirmed by a palpable tumour mass. He described gastric lavage in facilitating the palpation of the tumour, and distending the stomach with gas from Seidlitz powder as another diagnostic manoeuvre. Twenty-five years later, in 1916, he mentioned the finding of occult blood in the stool, and 'x-rays are sometimes an aid in diagnosis' (26 years after the discovery of x-rays by Roentgen, and approximately 10 years after Cannon's introduction to the use of barium). Osler also advocated the 'safety' of exploratory laparotomy in making the diagnosis. His 'Lectures on the Diagnosis of Abdominal Tumors' were published as a monograph in 1896, with at least two-thirds dealing with large tumours of the stomach. In this publication, he drew attention to the simultaneous occurrence of carcinoma of the ovary and the stomach (an early description of Krukenberg tumour). In 1902, he wrote a paper on the occurrence of ascites in solid abdominal tumours (8). There was one perplexing case described in the monograph of a tumour mass of 10 months' duration in the right iliac fossa which, at laparotomy, was shown to be 'an extensive new growth involving the cecum and extending a short distance into the ileum' (8). This may have been an early description of Crohn's disease." – Hugh Chaun, Canadian Journal of Gastroenterology. Golden & Roland 730. [HM] (Inventory #: M13492)
You can be confident that when you make a purchase through ABAA.org, the item is sold by an ABAA member in full compliance with our Code of Ethics. Our sellers guarantee your order will be shipped promptly and that all items are as described. Buy with confidence through ABAA.org.