Genevae,: Apud Samuelem de Tournes, 1681.. 358 x 232 mm. Large 4to. , 747,  pp. Title printed in red & black; title vignette, woodcut initial letters. Lacking frontis. portrait and half-title [both supplied in photocopy facs.], a few prick marks on title margins, usual occasional browning and spotting throughout. Modern quarter tan calf, marbled boards, white tips, maroon morocco spine label, new endleaves. Early ownership inscription: "Petri Martini Borrini, ... Michaelis Antonii Moni Gallieanensis." Nine line ink ms. inscription at final blank. Foot of title with initials "P.M.B." [=Petri Martini Borrini?]. Near fine. FIRST GENEVA EDITION, posthumously published edition of Sylvius� collected works, issued one year after the Amsterdam Opera Medica. He is known to be influenced by Paracelsus and an early supporter of William Harvey�s theory on the circulation of the blood. "Tuberculosis was known to the ancients only in its advanced form, and little progress was made in the knowledge of the condition until the time of Sylvius. He asserted that tubercles are often to be found in the lung and that they softened and suppurated to form cavities." Le Boe made his observations in 1650, but his De phthisi was published in his Opera in 1679. This edition of his collected works contains his writings in medical and chemical fields. Le Boe was an early and ardent supporter of Harvey�s theory of the circulation of the blood. � Contents: Disputationum Medicarum � De Methodo Medendi Liber I - ... Liber II - Praxeos medicae idea nova ... I � Liber II � De Morbis Infantum [on epidemics, pests, diseases] � Opuscula Varia � De Infimo Ventre Libr. I � De Media Cavitate Lib. II � De Suprema Cavitate Lib. III. � Francois de le Boe (1614-1672), Dutch physician, often known by his Latinized name, Franciscus Sylvius, was born in Hanau, Germany, studied medicine at the Protestant Academy of Sedan. He was a "very popular and respected" teacher at the University of Leiden. Among his most prominent students were DeGraaf (of graafian follicle fame); Stensen (of Stensen's duct fame); Swammerdam, who discovered red blood cells; and Van Horne, who discovered the thoracic duct in man. His most famous student was Thomas Bartholinus, who, during the process of updating the medical text written by his father, Caspar, first published [Francois] Sylvius� neuroanatomical work and very accurate description of the lateral cerebral sulcus" [op.cit.]. His description of neuroanatomy and especially the dural venous sinuses, are important contributions in the history of medicine. In creating the first academic chemical laboratory he "fathered the theoretical framework called iatrochemistry that modernized the Galenic humoral theory by integrating it with chemical information being discovered at the time." [op.cit.]. � Castiglioni, pp. 540-1; DSB, XIII, p. 223; Garrison and Morton 2321; Osler 4063; Partington II, pp. 281-90. (Inventory #: M0528)
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