15 pp. 8vo, stitched as issued (spine carefully backed with paper). N.p.: n.d. [letter dated at end "Edinburgh, April 1870"]. First printing of this letter which Simpson wrote in reply to an "attack" by Bigelow which had been published in the Boston Medical Journal. Simpson states, contrary to Bigelow's allegation, that he had never claimed "the introduction of chloroform as an anaesthetic in Edinburgh to be antecedent, in point of time, to the introduction of sulphuric ether in Boston." Nice copy. (Inventory #: 5512)
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