SIGNED. My Life in Science. As Told to Lewis Wolpert. Edited interview with additional material by Errol C. Friedberg and Eleanor Lawrence

London: BioMed Central Limited, 2001. Revised edition.

MOLECULAR BIOLOGIST AND NOBEL LAUREATE SYDNEY BRENNER IN HIS OWN WORDS: SIGNED COPY OF HIS TRANSCRIBED AUTOBIOGRAPHY AS TOLD TO COLLEAGUE LEWIS WOLPERT.

8 inches tall slim volume with color printed paper wraps, signed by Sydney Brenner on title page, v, 199 pp, fine in clear protective cover. FROM THE PREFACE: "This book has been produced from the transcript of a fifteen-hour videotaped autobiography, as told to Lewis Wolpert, Professor of Biology as Applied to Medicine, in the Department of Anatomy and Developmental Biology/ University College, London. In editing this transcript, we have strived to capture the highlights of Brenner's long and productive career as one of the pre-eminent biologists of the twentieth century. We have also attempted to capture much of the man - a man endowed with great wit and humour, a strong sense of irreverence, iconoclasm, and a profound appreciation of biology in its many and varied aspects."

CONTENTS: Growing up in South Africa; Seeing DNA; America and back again; Discovering messenger RNA; Deciphering the genetic code; DNA replication dissected; The challenge of higher organisms; How to do molecular biology in C. elegans; The evolution of genetics and the genetics of evolution; Endnotes.

SYDNEY BRENNER (1927-2019) was a South African biologist. In 2002, he shared the Nobel Prize in Physiology or Medicine with H. Robert Horvitz and Sir John E. Sulston. Brenner made significant contributions to work on the genetic code, and other areas of molecular biology while working in the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, England. He established the roundworm Caenorhabditis elegans as a model organism for the investigation of developmental biology, and founded the Molecular Sciences Institute in Berkeley, California. Following his PhD, Brenner did postdoctoral research at the University of California, Berkeley. He spent the next 20 years at the Laboratory of Molecular Biology in Cambridge. He was one of the first people in April 1953 to see the model of the structure of DNA, constructed by Francis Crick and James Watson; at the time he and the other scientists were working at the University of Oxford's Chemistry Department. In 1976 he joined the Salk Institute in California. Brenner founded the Molecular Sciences Institute in Berkeley, California in 1996. As of 2015 he was associated with the Salk Institute, the Institute of Molecular and Cell Biology, the Singapore Biomedical Research Council, the Janelia Farm Research Campus, and the Howard Hughes Medical Institute. In August 2005, He was also on the Board of Scientific Governors at The Scripps Research Institute, as well as being Professor of Genetics there.