CONTAINS CANNON'S FIRST USE OF "HOMEOSTASIS". A Charles Richet - ses amis, ses collegues, ses eleves. (n.p., Paris), May 1926. Bound with: Discours prononces a I'occasion du jubile Charles Richet.

Paris: Editions Medicales, 1926. First edition.

UNIQUE SIGNED ASSOCIATION COPY OF FESTSCHRIFT HONORING NOBELIST CHARLES RICHET, COPY OF NOBELIST CHARLES SHERRINGTON, CONTAINING WALTER CANNON'S ESSAY FIRST USING THE TERM "HOMEOSTASIS".

11 inches tall hardcover, gray cloth binding, gilt title to spine, (n.p., Paris), July 1926. There is a small handstamp at the bottom of the front paste-down, "Bound by Maltby Oxford." Two volumes in one, original stiff printed wrappers to both volumes bound in, uncut, [4],101 pp, [4]; 37 pp, [1]. Limitation indication in the first volume: copy 269 of 500, signed hy the editor. Each volume with the ownership signature of the 1932 Nobel laureate in physiology or medicine, C. S. Sherrington. Faint handstamp of institutional library to title page of each of the two volumes, overlaid "withdrawn". PAPERS IN FRENCH AND ENGLISH LANGUAGE.

Honored in this festschrift, CHARLES ROBERT RICHET (1850 –1935) was a French physiologist at the Collège de France known for his pioneering work in immunology. In 1913, he won the Nobel Prize in Physiology or Medicine "in recognition of his work on anaphylaxis". The Richet line of professorships of medical science would continue through his son Charles (whose contribution is included in the volume offered here) and his grandson Gabriel.

SIR CHARLES SHERRINGTON (1857-1952) was a British neurophysiologist who received the Nobel Prize in Physiology or Medicine in 1932 for his elucidation of the integrative action of the nervous system. On the verso of the front fly-leaf in Sherrington's hand is a listing of the two titles bound in this volume. Sherrington contributed a paper to the first volume (pp.88-90): Addition Latente and recruitinent in reflex contraction and inhibition. Faint library stamps of the Royal College of Surgeons. A very good copy.

Besides containing Sherrington's paper, this celebratory volume includes the original contributions of IVAN PAVLOV (Nobel 1904), BERNARDO ALBERTO HOUSSAY (Nobel 1947), SIR EDWARD ALBERT SHARPEY-SCHAFER (British physiologist who discovered adrenaline) and SIR OLIVER LODGE (British physicist who developed radio technology).

Notably, the volume also contains WALTER CANNON'S essay, Physiological regulation of normal states: Some tentative postulates concerning biological homeostasis (p. 91) that includes his first use of the term, "homeostasis," subsequently expanded in his book, The Wisdom of the Body (1932).

As early as 1895, Sherrington had tried to gain employment at Oxford University, and by 1913 Oxford offered Sherrington the Waynflete Chair of Physiology. Several of his students were Rhodes scholars, three of whom – Sir John Eccles, Ragnar Granit, and Howard Florey – went on to be Nobel laureates. Sherrington remained at Oxford until his retirement in 1936. He clearly treasured his copy of the Richet festschrift—Maltby's Bookbinders (established in 1834) continues to be Oxford's premier bookbinder.